Cyrille Sur Selected Research

Glycine Plasma Membrane Transport Proteins

1/2015	Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans.
1/2010	Recent progress in the discovery of non-sarcosine based GlyT1 inhibitors.
3/2009	Discovery of GlyT1 inhibitors with improved pharmacokinetic properties.
4/2008	A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies.
11/2004	Effects of typical and atypical antipsychotics on human glycine transporters.
10/2003	Development of a scintillation proximity assay for analysis of Na+/Cl- -dependent neurotransmitter transporter activity.

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Cyrille Sur Research Topics

Disease

10	Alzheimer Disease (Alzheimer's Disease) 12/2022 - 01/2006
10	Schizophrenia (Dementia Praecox) 01/2015 - 11/2003
4	Neoplasms (Cancer) 10/2010 - 08/2007
3	Amyloid Plaque 01/2021 - 07/2011
3	Choriocarcinoma 04/2008 - 10/2003
2	Disease Progression 01/2021 - 04/2019
2	Dementia (Dementias) 04/2019 - 01/2018
2	Cognitive Dysfunction 01/2010 - 05/2004
1	Atrophy 01/2021
1	Hemolysis 01/2020
1	Tauopathies 01/2020
1	Weight Loss (Weight Reduction) 01/2018
1	Wounds and Injuries (Trauma) 01/2018
1	Exanthema (Rash) 01/2018
1	Edema (Dropsy) 01/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2014
1	Neurogenic Inflammation 11/2013
1	Hypertension (High Blood Pressure) 08/2012
1	Inflammation (Inflammations) 01/2012
1	Atherosclerosis 01/2012
1	Obesity 02/2011
1	Migraine Disorders (Migraine) 04/2010
1	Memory Disorders (Memory Loss) 09/2009
1	Prostatic Neoplasms (Prostate Cancer) 09/2009
1	AIDS-Related Complex (ARC) 09/2009
1	Neurobehavioral Manifestations 01/2006
1	Psychotic Disorders (Schizoaffective Disorder) 11/2003

Drug/Important Bio-Agent (IBA)

7	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2010 - 11/2003
6	verubecestatIBA 12/2022 - 01/2017
6	Glycine Plasma Membrane Transport ProteinsIBA 01/2015 - 10/2003
5	Amyloid (Amyloid Fibrils)IBA 12/2022 - 11/2011
5	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2010 - 05/2004
5	N-Methylaspartate (NMDA)IBA 04/2008 - 11/2003
3	Antipsychotic Agents (Antipsychotics)IBA 11/2004 - 05/2004
2	EnzymesIBA 01/2021 - 08/2012
2	Pharmaceutical PreparationsIBA 04/2019 - 01/2009
2	Biomarkers (Surrogate Marker)IBA 01/2014 - 01/2012
2	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA 11/2013 - 04/2010
2	Calcitonin Gene-Related PeptideIBA 11/2013 - 04/2010
2	IntegrinsIBA 01/2012 - 10/2010
2	Peptide Hydrolases (Proteases)FDA Link 01/2012 - 10/2010
2	CathepsinsIBA 01/2012 - 10/2010
2	LigandsIBA 11/2011 - 07/2011
1	Retinaldehyde (Retinal)IBA 01/2021
1	flutemetamolIBA 01/2021
1	hexosaminidase CIBA 01/2020
1	MK-6240IBA 01/2020
1	tau Proteins (tau Protein)IBA 01/2020
1	Amyloid beta-PeptidesIBA 01/2018
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2017
1	Insulin (Novolin)FDA Link 01/2014
1	NeuropeptidesIBA 11/2013
1	AngiotensinogenIBA 08/2012
1	Angiotensin IIBA 08/2012
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 08/2012
1	ReninIBA 08/2012
1	Ezetimibe (Zetia)FDA Link 01/2012
1	Apolipoproteins E (ApoE)IBA 01/2012
1	Neuropeptide Y Receptors (Neuropeptide Y Receptor)IBA 02/2011
1	Coloring Agents (Dyes)IBA 10/2010
1	Tumor Biomarkers (Tumor Markers)IBA 10/2010
1	VitronectinIBA 10/2010
1	PeptidomimeticsIBA 10/2010
1	indeneIBA 04/2010
1	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 04/2010
1	acetamideIBA 04/2010
1	Inositol PhosphatesIBA 09/2009
1	Androgen Receptors (Androgen Receptor)IBA 09/2009
1	RNA (Ribonucleic Acid)IBA 09/2009
1	Scopolamine (Hyoscine)FDA Link 09/2009
1	AndrogensIBA 09/2009
1	Androgen Antagonists (Antiandrogens)IBA 09/2009
1	MTOR InhibitorsIBA 09/2009
1	Muscarinic AgonistsIBA 09/2009
1	Sirolimus (Rapamycin)FDA Link 09/2009
1	TOR Serine-Threonine KinasesIBA 09/2009
1	ErbB Receptors (EGF Receptor)IBA 01/2009
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2009
1	ginsenoside M1IBA 01/2009
1	Cre recombinaseIBA 01/2009
1	Irinotecan (Camptosar)FDA LinkGeneric 08/2007
1	Docetaxel (Taxotere)FDA Link 08/2007
1	LuciferasesIBA 08/2007
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2006
1	Dopamine (Intropin)FDA LinkGeneric 01/2006
1	Clozapine (Clozaril)FDA LinkGeneric 11/2003
1	norclozapineIBA 11/2003

Therapy/Procedure

5	Therapeutics 01/2012 - 01/2006
1	Activities of Daily Living (ADL) 01/2018
1	Immunotherapy 01/2017
1	Castration 09/2009